Current evidence-based recommendations on investigating children with global developmental delay

Current evidence-based recommendations on investigating children with global developmental delay

INTRODUCTION Global developmental delay (GDD) affects 1%-3% of the population of children under 5 years of age, making it one of the most common conditions presenting in paediatric clinics; causes are exogenous, genetic (non-metabolic) or genetic (metabolic). Recent advances in biotechnology and genetic testing mean that the investigations available to perform for children under 5 years are inc...

cns structural anomalies in iranian children with global developmental delay

how to cite this article: zamani gh, shervin badv r, niksirat a, alizadeh h. cns structural anomalies in iranian children with global developmental delay. iran j child neurol. 2013 winter; 7 (1):25-28.   objective central nervous system (cns) malformations are one of the most important causes of global developmental delay (gdd) in children. about one percent of infants with gdd have an inherite...

EVIDENCE BASED GUIDELINES Investigation of global developmental delay

CNS Structural Anomalies in Iranian Children with Global Developmental Delay

OBJECTIVE Central Nervous system (CNS) malformations are one of the most important causes of global developmental delay (GDD) in Children. About one percent of infants with GDD have an inherited metabolic disorder and 3-10 percent have a chromosomal disorder. This study aimed to survey the frequency of brain structural anomalies and their subtypes among the variety of etiologic factors in child...

Metabolic evaluation of children with global developmental delay

Global developmental delay (GDD) is a relatively common early-onset chronic neurological condition, which may have prenatal, perinatal, postnatal, or undetermined causes. Family history, physical and neurological examinations, and detailed history of environmental risk factors might suggest a specific disease. However, diagnostic laboratory tests, brain imaging, and other evidence-based evaluat...